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Vitamin C helps regenerate glutathione in the body and supports its antioxidant activity, which is why the two are so commonly administered together
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Notably, COF-909-Cu also displays GPx-like activity by depleting intracellular GSH, thereby suppressing H 2 O 2 scavenging and significantly elevating intracellular H 2 O 2 levels
In addition, studies also demonstrated that the C677T polymorphism of MTHFR is associated with onset age of schizophrenia in a dose-dependent manner, such as increasing numbers of the mutant T allele is linked with early onset 50
