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[2] [19] There is also a risk of gallbladder disease (cholelithiasis, cholecystitis), acute kidney injury secondary to dehydration from gastrointestinal effects, and rare but serious risks such as pancreatitis and thyroid C-cell tumours (observed in animal studies)

The Rising Costs and Competitive Landscape of GLP-1 Drugs Four GLP-1 drugs (Mounjaro, Ozempic, Saxenda, and Wegovy) account for 9% of overall prescription costs net of rebates per member per month (image below) 17

(2021) demonstrated that escalating doses were well-tolerated in humans with no dose-limiting toxicities

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The role of endogenous GLP-1 signaling in the lung is likely multifactorial and much more complex, particularly in a diseased state, and may depend on the mechanism of pulmonary injury