Except the positive control using in the kit, another two cases of Langerhans cell histiocytosis (LCH) which were previously confirmed with BRAF V600E mutation were also used as a positive control
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Equally, the 12-g dose ingested was higher than that typically used in CM research, therefore the changes in plasma citrulline concentration following the most common 8 g dose are unknown
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Understanding these alternatives requires context: not all patients respond identically to GLP-1 drugs, and genetic factors in peptide signaling can influence individual outcomes
