average weight loss with compounded semaglutide Results: What to Expect Get after your goal weight

Furthermore, some patients cannot tolerate injectable treatments, and GLP- 1 receptor agonist side effects typically depend on it

reinstated December 2025 (status: monitor closely) States that restrict coverage: Michigan restricted to BMI 40 (morbid obesity) with strict prior authorization criteria

The absence of GIP receptor activation may reduce cumulative gastrointestinal stress

However, early findings suggest that Retatrutide may offer slightly greater weight loss on average, with up to 24% of body weight lost compared to around 20% with Mounjaro

The most common side effects were mild to moderate gastrointestinal symptoms, such as nausea and vomiting, primarily associated with the first dose and substantially reduced with dose escalation