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CBD inhibits the enzymatic hydrolysis of AEA at the synaptic level, thereby enhancing endocannabinoid tone and promoting CB2R-dependent anti-neuroinflammatory, immunomodulatory, and antioxidant effects in the brain (Singh and Neary, 2020)

Epithelial cells, the essential physical barrier between the body and the environment, are prone to damage and even death when exposed to pollutants or allergens, which subsequently promote downstream immune responses [19, 20]

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