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A novel orally active water-soluble inhibitor of human glutathione transferase exerts a potent and selective antitumor activity against human melanoma xenografts

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40 Subsequently, researchers demonstrated that siRNA could be tailored to disrupt the expression of any pathogenic gene, propelling RNAi into the spotlight and fostering its active application in the treatment of various diseases

doi: 10.1016/j.febslet.2010.12.001 198 LinTChenYDingZLuoGLiuJShenJ