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Why It Works: GLP-1 and GIP reduce hunger and improve insulin sensitivity Glucagon receptor activation increases energy expenditure and fat oxidation 2

Important markers may include waist circumference, appetite control, energy, digestion, blood pressure, glucose markers, cholesterol, strength, and body composition goals

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Clinical trial data from the NEJM Phase 2 study showed that gastrointestinal events were predominantly mild to moderate, occurred primarily during dose escalation, and were partially mitigated by starting at 2mg rather than 4mg