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To better understand the clinical utility of flavonoids and assess their potential as adjunctive therapies, the following areas need to be further investigated: structural optimization, drug targeting, and inhalation delivery systems, standardized research reporting, and multi-omics data integration, along with rigorous multicenter clinical trials and comprehensive safety evaluations

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The ROOT MERISTEMLESS1/CADMIUM SENSITIVE2 gene defines a glutathione-dependent pathway involved in initiation and maintenace of cell division during postembryonic root development