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N Engl J Med 2023;389:222132.ArticlePubMed 73

GSH concentration is instead measured by either of two methods: by analysis of GS-NEM conjugates by HPLC in the same sample that is used to measure GSSG or, alternatively, by analysis of GSH by spectrophotometry (GSH recycling method) on one additional sample aliquot that has not been derivatized with NEM

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Their plasma urate dropped by 26.5 mol/L (about 8%) [13]

However, to date, there is no direct pathological and mechanical evidence to prove it