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Prolonged energy deficit and weight loss often reduce circulating insulin levels, and similar reductions in insulin have been observed for GLP1 agonist users

Among people who had ALS, those who had used such psychiatric drugs before diagnosis had the shortest survival time

Patients should proactively contact their GP or diabetes specialist nurse if they experience persistent or severe side effects at any dose, including ongoing nausea lasting beyond two weeks, repeated vomiting, severe abdominal pain, or signs of pancreatitis (severe upper abdominal pain radiating to the back)

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In the short term, there are sectors that are already seeing the effects, as explained by Francisco Rodrguez Fernndez, Economics professor at the University of Granada (UGR) and senior economist at Funcas, such as "food and beverages, where there is a clear reduction in calorie-dense and processed products." "But even in fashion, there is an increase in smaller sizes due to significant weight loss ." There are quantified analyses on this: sales of large women's shirts dropped by 11% between 2022 and 2024 , while smaller sizes grew by 12%