This is followed by maintenance injections of 1mg every 2-3 months (or every 2 months with neurological involvement)
B12 supplements are often used to treat or prevent deficiency, which can lead to symptoms such as fatigue, weakness, constipation, loss of appetite, and megaloblastic anemia
Hydroxocobalamin 1mg is the standard UK formulation, typically administered every two to three months for maintenance therapy Self-administration requires GP prescription, competency training from practice nurses, and demonstration of proper injection technique Common injection sites include the thigh (vastus lateralis) for both intramuscular and subcutaneous administration with site rotation essential Serious side effects are rare but anaphylaxis requires immediate 999 call
Shashikanth, N., Rizzo, H
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