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The only other study that has examined NPY in CF was conducted in the olfactory system, in which it was found that NPY was increased in the olfactory epithelium of CF mice [191]

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[1] Close monitoring and multidisciplinary support involving bariatric surgeons, endocrinologists, dietitians, and specialist nurses optimise treatment outcomes and ensure patient safety throughout the intervention

This aligns supplementation with the period of declining GLP-1 receptor occupancy while avoiding the peak nausea window that occurs Monday through Tuesday

Optimal outcomes require consistent adherence, gradual dose adjustments, and lifestyle alignment, avoiding mistakes like escalating doses too quickly or expecting immediate results