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Nesta abordagem individualizada e adaptada, os aGLP-1 so recomendados para pacientes fora do alvo glicmico com alto risco de desenvolvimento de doena cardiovascular, necessidade de perda ponderal e/ou meta de reduzir risco de hipoglicemia

A study of Semane and co-workers (2007) supports this finding [40]

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Resting metabolic rate can drop by 15%20% in people with untreated or undertreated hypothyroidism, meaning the body burns significantly fewer calories at rest than it would with normal thyroid function