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10.1007/BF02411460
Recent research breakthroughs have underscored the significance of integrative biomarkers that amalgamate several biological methodologies to improve diagnostic precision (156)
Here, we examine how a high-fat diet (HFD) that promotes AGE generation impairs male reproductive health in mice and evaluate two representative interventions with distinct mechanisms: Alagebrium (ALT-711), an AGE cross-link breaker 67 , and Fertilix, a commercial antioxidant fertility supplement 68
The rapid CHOP activation indicated that cytotoxicity of AQ-QI and DEAQ-QI was accompanied by the activation of the adaptive ER stress response pathway and subsequent activation of apoptotic programs (Tew and Townsend, 2012
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