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CSF levels of pros-methylimidazol acetic acid, an isomer of the histamine metabolite tele-methylimidazol acetic acid, have been found to be decreased in PD (Prell et al., 1991), and were highly positively correlated with the severity of the disease (Prell and Green, 1991)

Perimenopause is so deeply misunderstoodby women, society, everyonethat many of us have no idea were even in it when it happens

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References 1 WeyandCMGoronzyJJ

This framing is speculative but scientifically coherent with the known mechanisms