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Among phenolic acids, ferulic acid suffers from poor water solubility and limited bioavailability, while rosmarinic acid shows low gastrointestinal absorption (only 6.3% within 48 h) and is prone to metabolism by intestinal microbial esterases (Purushothaman and Rizwanullah, 2024
Furthermore, gut microbial communities have significant impacts on metabolic function and immune responses
Results Study Characteristics In this RCT, the efficacy of NAC on serum liver enzyme levels and metabolic profiles in patients with MASLD was evaluated over eight weeks
Targeting senescent hepatocytes using the thrombomodulin-PAR1 inhibitor vorapaxar ameliorates NAFLD progression
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