Due to the retrospective nature of the study, the researchers could not determine whether the reduction in BMI seen in the GLP-1 group was the primary driver contributing to visual improvement, and they determined that future studies may want to further explore this relationship
Correlation is not mechanism, and cross-trial comparisons are famously unreliable, but the trend has held up well enough that it now shapes how the whole field thinks about incretin design
The oral formulation requires specific administration on an empty stomach and may have variable absorption compared to injections
Before recommending any medication, I assess metabolic health markers including fasting insulin, HbA1c, thyroid function, and reproductive hormones
For the regulatory picture, see FDA peptide crackdown 2026