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Smaller stones may pass unnoticed in the urine, while larger stones can cause severe pain as they move through the urinary tract

Along with this, the lab applied mutagenesis and discovered plants with altered phenotypes, including the absence of derived cardenolides such as cannogenol and strophanthidin, presumably because of a mutation in a cytochrome P450 that hydroxylates digitoxigenin

While type 2 diabetes is not considered an autoimmune disease, scientists believe that patients with type 2 diabetes are at an increased risk of developing alopecia areata, which occurs when the body begins to attack its hair follicles