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On the other hand, the vicious course induced by high intra-abdominal pressure can be simultaneously initiated and perpetuated from different sites (it should be noted that intracranial hypertension may essentially cause pulmonary edema and impair pulmonary circulation (Chen, 2009))

Clinical therapy research demonstrates that supplementation with MI alone or in combination with DCI in a physiological ratio (typically 40:1) improves insulin sensitivity, lowers hyperinsulinemia, and enhances reproductive outcomes in PCOS patients, even in the absence of overt IR (140)