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Both hyperthyroidism and hypothyroidism are associated with increased percentage of abnormal sperm and decreased sperm concentration, sperm motility, and semen volume, possibly due in part to increased oxidative stress

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Unfortunately, studies on this topic have mainly focused on normalising serum B12 concentrations with oral supplementation and should be interpreted with caution since the specific goal of treatment in symptomatic B12 deficiency is alleviating symptoms, and NOT to normalize B12 concentrations in the blood