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Correction of the SAMe deficiency that is characteristic of the AD brain may attenuate or prevent pathological processes driving AD-associated neurodegeneration including aberrant tau hyperphosphorylation and DNA hypomethylation

Its a simple but critical concept: any compound powerful enough to create a positive biological change is also powerful enough to cause other, unintended changes

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DOI: 10.1007/s13410-021-00933-9 66

Le condizioni mediche che solitamente suggeriscono lintegrazione di carnitina sono : gravi patologie epatiche e renali obesit diabete restrizione calorica nascita pretermine digiuno prolungato Il dosaggio quotidiano di L-carnitina si aggira in genere tra i 500 e i 2000 mg , ma non esiste una quantit valida per tutti