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A p-value less than 0.05 was considered statistically significant, indicating a meaningful difference in treatment efficacy

Continuous daily use is not recommended due to the potential for receptor desensitization

In vitro studies revealed that GPER agonist-treated hepatocytes exhibit improved survival and reduced fat accumulation under lipotoxic conditions, underscoring the role of GPER in protecting against lipotoxicity [34]

However, it must be noted here that this population study was performed with a much lesser number of individuals

Insert the needle at a 45 to 90 degree angle (45 degrees for lean individuals, 90 degrees for those with more subcutaneous fat)