Crystalloids are aqueous solutions of mineral salts or other water-soluble molecules
S is the main component of Lewy bodies and is a pathogenic feature of all synucleinopathies, including Parkinsons disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA)
Authors contributions Conceptualization and methodoloy preparation, project administration, writing original draft: Kobayashi H Software preparation: Kobayashi H, Matsubara S, Yoshimoto C, Imanaka S Validation: Yoshimoto C, Shigetomi H, Imanaka S Formal analysis and investigation: Matsubara S, Yoshimoto C, Shigetomi H, Imanaka S Resources provided and supervision: Matsubara S Data curation: Matsubara S, Kobayashi H Writing, review, editing and visualization: Kobayashi H, Matsubara S, Yoshimoto C, Shigetomi H, Imanaka S Funding acquisition: Yoshimoto C Availability of data and materials Not applicable
Due to the negative feedback by IGF-1 on the hypothalamus, growth hormone (GH) levels decrease significantly
Adjust injection timing (morning versus evening) finding better tolerated time
