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While older peptides like GHRP-2 and GHRP-6 also stimulate GH, they often raise levels of cortisol and prolactin , leading to unwanted effects like bloating, anxiety, or gynecomastia

A qualified provider can integrate genetic context, clinical history, and tolerability goals to select and schedule the most appropriate therapy

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Effects on the Brain and Circadian Rhythm GLP-1 receptors are present in parts of the brain that regulate: Sleep-wake cycles Hormone release Stress response Energy balance When semaglutide activates these pathways, the body may temporarily adjust its sleep rhythm

Jul 13 5 min read GLP-1 medications have changed the weight loss conversation