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[2] Raun K, Hansen BS, Johansen NL, Thgersen H, Madsen K, Ankersen M, Andersen PH

Vitamin B12-induced hyperpigmentation is usually treatable based on administered nutritional supplements and proper care

A study has found that neurotransmitters from the intestine act on the brain through blood circulation, local stimulation of the intestinal nervous system, and rapid signal transduction of the vagus nerve ( 4.5 Regulating HPA axis The HPA axis is one of the main neuroendocrine systems that respond to stress, and can produce glucocorticoids, participate in cognitive processes such as neural development, learning and memory

Dale Shepard, MD, PhD: So essentially sort of sucking up that complex so it can't work,- Ofer Reizes, PhD: Right

Always call your pharmacy or physician/clinic for clarification