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doi: 10.1007/s11356-019-04585-5 166 CharronMJWilliamsLSekiYDuXQChaurasiaBSaghatelianAet al

Proton Pump Inhibitors, H2-Receptor Antagonists, Metformin, and Vitamin B-12 Deficiency: Clinical Implications

The data is striking: in a Phase 2 trial published in the New England Journal of Medicine, the highest doses produced an average ~24% body-weight reduction at 11 months more than any currently approved weight-loss drug (American Diabetes Association)

The side effects of BPC-157 are not fully documented due to its investigational status, but current research and anecdotal reports suggest it is generally well-tolerated

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