doi: 10.3389/fphar.2021.777395
Quantitative assessment of MF remains a significant challenge in both clinical and preclinical research, hindered by technical limitations and the inherent variability of the disease (Barton et al., 2023
The two cysteines in this motif catalyze glutathione (GSH)-dependent thiol-disulfide exchange reactions, i.e., the reduction of protein disulfides and, with high specificity, reversible (de-)glutathionylation [19] Oxidized Grxs are reduced by GSH, the resulting GSH disulfide (GSSG) by glutathione reductase (GR) using NADPH as electron source [20]
In addition, JEV infection promoted the expression of YAP1 that was the upstream of ACSL4 in SH-SY5Y cells (Cottini et al., 2014)
Semaglutide protects against 6-OHDA toxicity by enhancing autophagy and inhibiting oxidative stress