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Gynecol.Oncol 2012;124(3):417-425

GLP-1s improve systemic insulin sensitivity, reduce vascular inflammation, enhance endothelial function, and modestly lower blood pressure collectively improving blood flow and nutrient delivery to the brain [12]

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It is unknown whether the abnormally increased biosynthesis of melanin is the outcome of an early biopathological process in the development of oral mucosal melanoma, playing a role in the initial transformational events of melanocytes, or whether it is a manifestation of a malignant phenotype arising subsequently to the malignant transformation of normal melanocytes