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Olpasiran and lepodisiran are GalNAc conjugates containing siRNAs that target the LPA gene, promoting RISC-mediated degradation of Apo(a) mRNA and preventing Lp(a) particle assembly in hepatocytes

Mounjaro lawsuits have been filed against manufacturer Eli Lilly by people who allege serious gastrointestinal health issues like gastroparesis (stomach paralysis)