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As ongoing research continues to refine our understanding, evidence-based counseling remains the best tool for guiding safe and effective treatment decisions

Nevertheless, LDH5 inhibition had no significant effect on TGF-1-mediated transformation of fibroblasts to myofibroblasts in primary human lung fibroblasts, suggesting that the LDH5-dependent metabolic shift to aerobic glycolysis alone is not the decisive factor (214)

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Lastly, induction of CYP2B, 2C, and 3A was evaluated immunochemically by immunoblotting in male and female patas and cynomologus monkeys treated with phenobarbital (Jones and Lubet 1992)