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We also highlight existing gaps in research, future directions, and broader implications related to the potential use of GLP-1RAs for addiction treatment

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Novo Nordisk A/S, Eli Lilly and Company, AstraZeneca plc, Sanofi S.A., Merck & Co., Inc., Boehringer Ingelheim International GmbH, and Zealand Pharma A/S are global key players in the market

In conclusion, tirzepatide increased blood pressure and sympathetic activity in hypertensive rats without cardiac protection, highlighting context-dependent cardiovascular actions

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