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An epidemiologic study by Apnimed, a clinical-stage pharmaceutical company developing AD109, an oral drug candidate for OSA, demonstrated that most people with OSA60.6%are not obese
Thats 12 percent of adults, which is a lot of people
IGFBP-3, a secreted glycoprotein, can regulate the mitogenic activity of IGF-1R
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Notably, conventional hemodialysis fails to efficiently clear IS due to its protein-binding property, resulting in persistently elevated concentrations in CKD patients compared to healthy individuals (Ahmed et al., 2013a
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