StatPearls notes that high-dose oral B has been shown effective for maintenance, but recommendations are to always use the parenteral route in severe neurological manifestations
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The C16, C18 and C16OH acylcarnitine concentrations in the blood of congenital hypothyroid patients were significantly lower than that of the healthy control participants with C16, C18 and C16OH acylcarnitine concentrations of 1.24 0.43, 0.47 0.17 and 0.01 0.003 mol/L, respectively and the differences between the two groups produced significant P values of 0.0003, 0.002 and 0.001, respectively (Table 3)
To our delight, it was possible to generate the aryl-fused BCHep framework 16 (functioning as isosteres of 17 ) via an iridium-catalysed [2+2] photocycloaddition through visible light-induced energy transfer, adapting the methodology developed by Kwon and coworkers 30