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Ultra-processed foods take up stomach space without providing meaningful nutrition leading to measurable micronutrient deficiencies within weeks of starting a GLP-1

Improvements in heart failure outcomes with GLP-1 receptor agonists have thus far been demonstrated only with specific agents such as subcutaneous semaglutide [25], the first in class dual glucose-dependent insulinotropic polypeptide/GLP-1 receptor agonist tirzepatide [26], as well as the nonsteroidal mineralocorticoid receptor antagonist finerenone [27]

Glucagon-like peptide-1 (GLP-1) is a hormone naturally produced in cells of the intestine

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Semaglutide activates GLP-1 receptors throughout the pancreas, gastrointestinal tract, and central nervous system to enhance glucose-dependent insulin release, further slow gastric emptying, and reduce food intake through hypothalamic and brainstem circuits