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On the other hand, RWE lacks the ability to establish causality by minimising confounding effects which is a key strength of randomised clinical trials (RCTs)

doi: 10.1038/nature24661 118 LamasBRichardMLLeducqVPhamHPMichelMLDa CostaGet al

A gastric inhibitory polypeptide

Meanwhile, research on the mechanism and efficacy of GLP-1R/GIPR dual agonists and GLP-1R/GIPR/GCGR triple agonists paves the way to a ground-breaking therapy specific for obesity, which suggests multi-target drugs may have more advantages than a single target