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Semaglutide, a GLP-1 receptor agonist, can lead to significant initial weight loss

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reported a global pooled prevalence of MASLD (detected by liver imaging or biopsy) of 65.3 % (95 % confidence interval 62.3 %-68.2 %) (Younossi et al., 2024[87])

Contact your healthcare provider if fatigue is severe or persistent, interferes with daily activities, or is accompanied by signs of hypoglycemia, dehydration, severe abdominal pain, persistent vomiting, or other concerning symptoms that may indicate serious adverse effects requiring medical evaluation

2.4 Statistical analysis The AE reports were analyzed for signal detection using two-by-two contingency tables (Table 1) and four algorithms: the ROR, the PRR, the BCPNN, and the EBGM (shown in Supplementary Table S2)