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Diabetes 53(9):24922500 Balkan B, Li X (2000) Portal GLP-1 administration in rats augments the insulin response to glucose via neuronal mechanisms

No single canonical receptor binds the peptide with high affinity, and the systems-level pharmacology that defines the compound continues to be an active research question

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Under stirring, the suspension is gradually cooled to +l6C in two hours, then to +4/8C in one hour

Human research has made that conclusion less certain