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Depending on the signals received in the plaque microenvironment, recruited monocytes can assume variety of macrophage identities including inflammatory macrophages, aortic intima-resident macrophages (Mac AIR ), and type I interferon-inducible cells

High-protein, moderate-fiber meals in smaller portions are the foundation

GLP1 receptor agonists can assist with this through increasing insulin secretion and decreasing glucagon production, leading to improved overall glycemic control

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The compound engages the NAD+ pool from the opposite direction as NAD+ supplementation slowing removal rather than adding to the pool