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Different Timing of LANTUS Administration in Diabetes Type 1 and Diabetes Type 2 The safety and efficacy of once daily LANTUS administered either at pre-breakfast, pre-dinner, or at bedtime were evaluated in a randomized, controlled clinical study in adult patients with type 1 diabetes (Study H, n=378)

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That is why all patients treated on this study will get their own stem cells given back after the BSO/melphalan to decrease the side effects on the blood cells