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Interestingly, hyperplasia of selected EEC subtypes in response to intestinal infection is probably dependent on immune cells, since serotonin (5-HT)-producing cell hyperplasia associated with Citrobacter rodentium infection was absent in mice lacking adaptive immunity (53) and CD4 + T cells were necessary to increase numbers of 5-HT producing enterochromaffin cells during helminth infection (149)

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10.3389/fphar.2019.00457 40 MahataS

It is thus, difficult to know whether the alteration of the BBB is a cause or a consequence or both of the related neurological pathology

During consultation, your doctor will check your previous medical records and take a detailed history to assess your suitability for treatment