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Medline Plus recommends each dose of the XL version be taken at least 24 hours apart
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Psychiatric symptoms agitation, hallucinations, tremors, or significant mood changes Signs of dependence or tolerance escalating dose requirements, persistent use beyond therapeutic need Managing side effects Always take phentermine in the morning to minimize sleep disruption Stay well hydrated throughout the day to reduce dry mouth Monitor your blood pressure regularly during the first weeks of treatment Avoid caffeine, which can amplify stimulant side effects including increased heart rate and insomnia Report any chest pain, shortness of breath, or significant mood changes to your prescriber immediately Do not increase your dose without prescriber guidance Diet, lifestyle, and phentermine Diet on phentermine Phentermine is most effective when paired with a structured, reduced-calorie eating plan
Brain development continues after birth (Stiles & Jernigan, 2010
