Structure of GPX4 U46C-K48L is based on crystal structure reported in this work
Synthesis Add 96g of acetic acid to the reaction vessel, add 32g of levulinic acid to dissolve under stirring, when completely dissolved, add 61.5g of acetic anhydride, then raise the temperature to 80 constant temperature reaction for 12 hours, the reaction is completed, in a vacuum of -0.09Mpa, the temperature of 80 below the distillation of acetic acid removal, reduce the temperature to 40 , add 160g of acetone, fully stirred and dispersed for 0.5 hours, reduced temperature to 5 below precipitation of crystals, and held between 0 ~ 5 for 2 hours, filtration and separation, wash the solid with acetone, in a vacuum -0.09 Mpa, dried at 80 , that is to obtain acetyl levulinic acid 36g finished product, yield 88.9%
Separate aliquots were reserved for positive and negative ionization modes
You should always ask your vet for approval before giving this supplement to your pet
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