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Evaluate whether dietary factors or decreased activity explain the plateau rather than medication failure

Furthermore, proBDNF could serve as a reservoir for the mature molecule, and an increase in proBDNF suggests a larger BDNF deposit that is likely associated with greater genetic transcription (e.g., epigenetic regulation)

However, as weight loss is also associated with enhanced physical fitness, these observed effects may not be attributed solely to growth hormone treatment

The pineal gland also has a secondary influence on reproductive hormones, particularly in seasonal breeders in the animal kingdom, although the significance of these findings in humans remains under investigation

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