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GLP1 agonist therapy may be used to address medically supervised weight reduction, obesity-related comorbidities, and longer-term weight management in appropriately evaluated patients

Researchers believe this may be due to how GLP-1 affects the gut by: Slowing motility Modulating nerve signaling Possibly reducing visceral hypersensitivity (pain response) There is also some early evidence that GLP-1 medications may reduce overall IBS symptom severity and medication use, although more long-term data is needed 6

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