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ALKBH5 mechanistically reduced the stability of ACSL4 mRNA through m6A demethylation in a manner that was reliant on YTHDF1
doi:10.1056/NEJMoa2416394 Ayesh H, Suhail S, Ayesh S, Niswender K
In a review of racial and ethnic differences in obesity outcomes of lifestyle, surgical, and pharmacological interventions published between 2000 and 2022, lower efficacy of lifestyle and surgical interventions was commonly identified among Black compared with White participants (with no or smaller differences for Hispanic compared with White participants)
The distinction matters, because the headline nausea percentages sound far more alarming than the discontinuation data warrants
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