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In murine models of melanoma and colorectal cancer, simvastatin stimulates antitumor immune responses on its own and improves responses to -PD1 immunotherapy, accompanied by an increase in intratumoral lipid peroxidation

Persistently high TSH causes thyroid hypertrophy (goiter)

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Adrian, S., Scherzinger, A., Sanyal, A., Lake, J.E., Falutz, J., Dub, M.P., Stanley, T.L., Grinspoon, S.K., Mamputu, J., Marsolais, C., Brown, T.T., & Erlandson, K.M