The conversion factor is not used to calculate the ASC payment rates for separately payable services that are assigned status indicators other than payment indicators A2, D2, G2, J8, P2, R2, and Z2. These services include separately payable drugs and biologicals, pass-through devices that are contractor-priced, brachytherapy sources that are paid based on the OPPS payment rates, and certain office-based procedures, radiology services, and diagnostic tests where payment is based on the PFS nonfacility PE RVU-based amount, and a few other specific services that receive cost-based payment (77 FR 68500)
Decrease dose if: Experiencing consistent side effects (headaches, fatigue, GI disturbance), achieving satisfactory results at current dose with no need for escalation, or cost considerations favor using minimum effective dose
This includes not just assessing the primary endpoints of your study, but also general health markers, organ function indicators, and behavioral observations
See the regulatory hub
Is BPC-157 Checked in Military Drug Tests