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Phase 3 trials (large human trials with thousands of participants) are still running, and Lilly plans to apply for regulatory approval once the TRIUMPH programme publishes its results across 2026

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(Gallstones can also result from rapid weight loss in the absence of GLP-1 medication.) Thyroid tumors: Animal studies have raised concerns about a potential link between GLP-1s and thyroid tumors, but ongoing surveillance has not shown that this applies to humans

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doi: 10.3390/metabo11030155

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