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Under normal circumstances, collateral vessels enlarge gradually over weeks to months in response to sustained ischemia

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These include: fatigue (low energy) dizziness injection site reactions, such as discomfort or skin discoloration small increase in heart rate changes in how things taste, such as having a bitter, metallic, or sour taste in your mouth digestive problems, such as: abdominal pain constipation or diarrhea flatulence (gas) or burping nausea and vomiting upset stomach Medical Perspective GLP-1 agonists may cause fatigue and other side effects