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According to a study published in PubMed Central (National Institutes of Health), intravenous administration of vitamin B12 provides a faster increase in B12 levels compared to oral supplementation, making it a potentially better option for patients with severe deficiency

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Folate Health Professional Fact Sheet.

[37] The MMACHC gene product is characterised as a cyanocobalamin reductase (cyanide-eliminating) and an alkylcobalamin reductase